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Mouse intestinal microbiota reduction favors local intestinal immunity triggered by antigens displayed in Bacillus subtilis biofilm

BACKGROUND: We previously engineered Bacillus subtilis to express an antigen of interest fused to TasA in a biofilm. B. subtilis has several properties such as sporulation, biofilm formation and probiotic ability that were used for the oral application of recombinant spores harboring Echinococcus gr...

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Detalles Bibliográficos
Autores principales: Vogt, Cédric M., Hilbe, Monika, Ackermann, Mathias, Aguilar, Claudio, Eichwald, Catherine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6258259/
https://www.ncbi.nlm.nih.gov/pubmed/30477481
http://dx.doi.org/10.1186/s12934-018-1030-8