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Merkel cell polyomavirus-specific immune responses in patients with Merkel cell carcinoma receiving anti-PD-1 therapy

BACKGROUND: Merkel cell carcinoma (MCC) is an aggressive skin cancer that frequently responds to anti-PD-1 therapy. MCC is associated with sun exposure and, in 80% of cases, Merkel cell polyomavirus (MCPyV). MCPyV-specific T and B cell responses provide a unique opportunity to study cancer-specific...

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Detalles Bibliográficos
Autores principales: Miller, Natalie J., Church, Candice D., Fling, Steven P., Kulikauskas, Rima, Ramchurren, Nirasha, Shinohara, Michi M., Kluger, Harriet M., Bhatia, Shailender, Lundgren, Lisa, Cheever, Martin A., Topalian, Suzanne L., Nghiem, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6258401/
https://www.ncbi.nlm.nih.gov/pubmed/30482247
http://dx.doi.org/10.1186/s40425-018-0450-7