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Role of TLR4-p38 MAPK-Hsp27 signal pathway in LPS-induced pulmonary epithelial hyperpermeability

BACKGROUND: The breakdown of alveolar barrier dysfunction contributes to Lipopolysaccharide stimulated pulmonary edema and acute lung injury. Actin cytoskeleton has been implicated to be critical in regulation of epithelial barrier. Here, we performed in vivo and in vitro study to investigate role o...

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Detalles Bibliográficos
Autores principales:	Wang, Weiju, Weng, Jie, Yu, Lei, Huang, Qiaobing, Jiang, Yong, Guo, Xiaohua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6258407/ https://www.ncbi.nlm.nih.gov/pubmed/30482200 http://dx.doi.org/10.1186/s12890-018-0735-0

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