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MNAT1 is overexpressed in colorectal cancer and mediates p53 ubiquitin-degradation to promote colorectal cancer malignance

BACKGROUND: MNAT1 (menage a trois 1, MAT1), a cyclin-dependent kinase-activating kinase (CAK) complex, high expresses in various cancers and is involved in cancer pathogenesis. However, mechanisms underlying its regulation in carcinogenesis are unclear. METHODS: The tissue microarray of colorectal c...

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Detalles Bibliográficos
Autores principales:	Zhou, Shan, Lu, Jinping, Li, Yuejin, Chen, Chan, Cai, Yongqiang, Tan, Gongjun, Peng, Zhengke, Zhang, Zhenlin, Dong, Zigang, Kang, Tiebang, Tang, Faqing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6258412/ https://www.ncbi.nlm.nih.gov/pubmed/30477538 http://dx.doi.org/10.1186/s13046-018-0956-3

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