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A metabolome-wide characterization of the diabetic phenotype in ZDF rats and its reversal by pioglitazone
Type 2 diabetes (T2D) is a complex metabolic disease associated with alterations in glucose, lipid and protein metabolism. In order to characterize the biochemical phenotype of the Zucker diabetic fatty (ZDF) rat, the most common animal model for the study of T2D, and the impact of the insulin sensi...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6258476/ https://www.ncbi.nlm.nih.gov/pubmed/30481177 http://dx.doi.org/10.1371/journal.pone.0207210 |