Abnormally elevated USP37 expression in breast cancer stem cells regulates stemness, epithelial-mesenchymal transition and cisplatin sensitivity

BACKGROUND: Recent studies have indicated that deubiquitinating enzymes (DUBs) are related to the stem-cell pathway network and chemo-resistance in cancer. Ubiquitin-specific peptidase 37 (USP37), a novel DUB, was identified to be a potential factor associated with tumor progression. However, the bi...

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Detalles Bibliográficos
Autores principales: Qin, Tao, Li, Bai, Feng, Xiaoyue, Fan, Shujun, Liu, Lei, Liu, Dandan, Mao, Jun, Lu, Ying, Yang, Jinfeng, Yu, Xiaotang, Zhang, Qingqing, Zhang, Jun, Song, Bo, Li, Man, Li, Lianhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6258492/
https://www.ncbi.nlm.nih.gov/pubmed/30482232
http://dx.doi.org/10.1186/s13046-018-0934-9

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