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Dual HLA B*42 and B*81-reactive T cell receptors recognize more diverse HIV-1 Gag escape variants
Some closely related human leukocyte antigen (HLA) alleles are associated with variable clinical outcomes following HIV-1 infection despite presenting the same viral epitopes. Mechanisms underlying these differences remain unclear but may be due to intrinsic characteristics of the HLA alleles or res...
Autores principales: | Ogunshola, Funsho, Anmole, Gursev, Miller, Rachel L., Goering, Emily, Nkosi, Thandeka, Muema, Daniel, Mann, Jaclyn, Ismail, Nasreen, Chopera, Denis, Ndung’u, Thumbi, Brockman, Mark A., Ndhlovu, Zaza M |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6258674/ https://www.ncbi.nlm.nih.gov/pubmed/30479346 http://dx.doi.org/10.1038/s41467-018-07209-7 |
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