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Pd(OAc)(2)-catalyzed asymmetric hydrogenation of sterically hindered N-tosylimines

Asymmetric hydrogenation of sterically hindered substrates still constitutes a long-standing challenge in the area of asymmetric catalysis. Herein, an efficient palladium acetate (an inexpensive Pd salt with low toxicity) catalyzed asymmetric hydrogenation of sterically hindered N-tosylimines is rea...

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Detalles Bibliográficos
Autores principales: Chen, Jianzhong, Zhang, Zhenfeng, Li, Bowen, Li, Feilong, Wang, Yulin, Zhao, Min, Gridnev, Ilya D., Imamoto, Tsuneo, Zhang, Wanbin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6258694/
https://www.ncbi.nlm.nih.gov/pubmed/30479338
http://dx.doi.org/10.1038/s41467-018-07462-w