Isolation, identification, structural elucidation and bioactivity of Heneicos-1-ene from Coriandrum sativum L. foliage

Coriander foliage is a distinctive spice employed on a daily basis in curry and other Indian traditional food preparations mainly for the unique flavour attributes and health benefits. Radical scavenging activity has been demonstrated previously for coriander foliage. However, specific molecules res...

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Autores principales: Priyadarshi, Siddharth, Harohally, Nanishankar V., Roopavathi, C., Naidu, Madeneni Madhava
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6258703/
https://www.ncbi.nlm.nih.gov/pubmed/30479370
http://dx.doi.org/10.1038/s41598-018-35836-z
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author Priyadarshi, Siddharth
Harohally, Nanishankar V.
Roopavathi, C.
Naidu, Madeneni Madhava
author_facet Priyadarshi, Siddharth
Harohally, Nanishankar V.
Roopavathi, C.
Naidu, Madeneni Madhava
author_sort Priyadarshi, Siddharth
collection PubMed
description Coriander foliage is a distinctive spice employed on a daily basis in curry and other Indian traditional food preparations mainly for the unique flavour attributes and health benefits. Radical scavenging activity has been demonstrated previously for coriander foliage. However, specific molecules responsible were not identified. A new molecule was isolated via chromatographic technique, and its structure was established by employing multinuclei and multidimensional NMR and HRMS techniques. The identified molecule Heneicos-1-ene was also screened for radical scavenging activity and antimicrobial activity, wherein it displayed radical scavenging activity of 89.6 ± 0.62% at 200 ppm, and also exhibited substantial antimicrobial activity against E. coli and Salmonella typhi.
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spelling pubmed-62587032018-12-03 Isolation, identification, structural elucidation and bioactivity of Heneicos-1-ene from Coriandrum sativum L. foliage Priyadarshi, Siddharth Harohally, Nanishankar V. Roopavathi, C. Naidu, Madeneni Madhava Sci Rep Article Coriander foliage is a distinctive spice employed on a daily basis in curry and other Indian traditional food preparations mainly for the unique flavour attributes and health benefits. Radical scavenging activity has been demonstrated previously for coriander foliage. However, specific molecules responsible were not identified. A new molecule was isolated via chromatographic technique, and its structure was established by employing multinuclei and multidimensional NMR and HRMS techniques. The identified molecule Heneicos-1-ene was also screened for radical scavenging activity and antimicrobial activity, wherein it displayed radical scavenging activity of 89.6 ± 0.62% at 200 ppm, and also exhibited substantial antimicrobial activity against E. coli and Salmonella typhi. Nature Publishing Group UK 2018-11-27 /pmc/articles/PMC6258703/ /pubmed/30479370 http://dx.doi.org/10.1038/s41598-018-35836-z Text en © The Author(s) 2018 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Article
Priyadarshi, Siddharth
Harohally, Nanishankar V.
Roopavathi, C.
Naidu, Madeneni Madhava
Isolation, identification, structural elucidation and bioactivity of Heneicos-1-ene from Coriandrum sativum L. foliage
title Isolation, identification, structural elucidation and bioactivity of Heneicos-1-ene from Coriandrum sativum L. foliage
title_full Isolation, identification, structural elucidation and bioactivity of Heneicos-1-ene from Coriandrum sativum L. foliage
title_fullStr Isolation, identification, structural elucidation and bioactivity of Heneicos-1-ene from Coriandrum sativum L. foliage
title_full_unstemmed Isolation, identification, structural elucidation and bioactivity of Heneicos-1-ene from Coriandrum sativum L. foliage
title_short Isolation, identification, structural elucidation and bioactivity of Heneicos-1-ene from Coriandrum sativum L. foliage
title_sort isolation, identification, structural elucidation and bioactivity of heneicos-1-ene from coriandrum sativum l. foliage
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6258703/
https://www.ncbi.nlm.nih.gov/pubmed/30479370
http://dx.doi.org/10.1038/s41598-018-35836-z
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