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PTEN expression by an oncolytic herpesvirus directs T-cell mediated tumor clearance

Engineered oncolytic viruses are used clinically to destroy cancer cells and have the ability to boost anticancer immunity. Phosphatase and tensin homolog deleted on chromosome 10 loss is common across a broad range of malignancies, and is implicated in immune escape. The N-terminally extended isofo...

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Detalles Bibliográficos
Autores principales:	Russell, Luke, Swanner, Jessica, Jaime-Ramirez, Alena Cristina, Wang, Yufeng, Sprague, Alex, Banasavadi-Siddegowda, Yeshavanth, Yoo, Ji Young, Sizemore, Gina M., Kladney, Raleigh, Zhang, Jianying, Lehman, Norman L., Ostrowski, Michael C, Hong, Bangxing, Caligiuri, Michael, Yu, Jianhua, Kaur, Balveen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6258708/ https://www.ncbi.nlm.nih.gov/pubmed/30479334 http://dx.doi.org/10.1038/s41467-018-07344-1

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