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Transdifferentiating Astrocytes Into Neurons Using ASCL1 Functionalized With a Novel Intracellular Protein Delivery Technology

Cellular transdifferentiation changes mature cells from one phenotype into another by altering their gene expression patterns. Manipulating expression of transcription factors, proteins that bind to DNA promoter regions, regulates the levels of key developmental genes. Viral delivery of transcriptio...

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Detalles Bibliográficos
Autores principales:	Robinson, Meghan, Fraser, Ian, McKee, Emily, Scheck, Kali, Chang, Lillian, Willerth, Stephanie M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Bioengineering and Biotechnology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6258721/ https://www.ncbi.nlm.nih.gov/pubmed/30525033 http://dx.doi.org/10.3389/fbioe.2018.00173

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