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Cisplatin treatment induces attention deficits and impairs synaptic integrity in the prefrontal cortex in mice

Patients treated for cancer frequently experience chemobrain, characterized by impaired memory and reduced attention. These deficits often persist after treatment, and no preventive or curative interventions exist. In mice, we assessed the effect of cisplatin chemotherapy on attention using the 5-ch...

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Detalles Bibliográficos
Autores principales: Huo, XiaoJiao, Reyes, Teresa M., Heijnen, Cobi J., Kavelaars, Annemieke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6258730/
https://www.ncbi.nlm.nih.gov/pubmed/30479361
http://dx.doi.org/10.1038/s41598-018-35919-x