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Cisplatin treatment induces attention deficits and impairs synaptic integrity in the prefrontal cortex in mice
Patients treated for cancer frequently experience chemobrain, characterized by impaired memory and reduced attention. These deficits often persist after treatment, and no preventive or curative interventions exist. In mice, we assessed the effect of cisplatin chemotherapy on attention using the 5-ch...
Autores principales: | Huo, XiaoJiao, Reyes, Teresa M., Heijnen, Cobi J., Kavelaars, Annemieke |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6258730/ https://www.ncbi.nlm.nih.gov/pubmed/30479361 http://dx.doi.org/10.1038/s41598-018-35919-x |
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