Slx5-Slx8 ubiquitin ligase targets active pools of the Yen1 nuclease to limit crossover formation

The repair of double-stranded DNA breaks (DSBs) by homologous recombination involves the formation of branched intermediates that can lead to crossovers following nucleolytic resolution. The nucleases Mus81-Mms4 and Yen1 are tightly controlled during the cell cycle to limit the extent of crossover f...

Descripción completa

Detalles Bibliográficos
Autores principales: Talhaoui, Ibtissam, Bernal, Manuel, Mullen, Janet R., Dorison, Hugo, Palancade, Benoit, Brill, Steven J., Mazón, Gerard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6258734/
https://www.ncbi.nlm.nih.gov/pubmed/30479332
http://dx.doi.org/10.1038/s41467-018-07364-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6258734/
https://www.ncbi.nlm.nih.gov/pubmed/30479332
http://dx.doi.org/10.1038/s41467-018-07364-x

Ejemplares similares