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MFF-dependent mitochondrial fission regulates presynaptic release and axon branching by limiting axonal mitochondria size

Neurons display extreme degrees of polarization, including compartment-specific organelle morphology. In cortical, long-range projecting, pyramidal neurons (PNs), dendritic mitochondria are long and tubular whereas axonal mitochondria display uniformly short length. Here we explored the functional s...

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Detalles Bibliográficos
Autores principales: Lewis, Tommy L., Kwon, Seok-Kyu, Lee, Annie, Shaw, Reuben, Polleux, Franck
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6258764/
https://www.ncbi.nlm.nih.gov/pubmed/30479337
http://dx.doi.org/10.1038/s41467-018-07416-2

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