Limited Marginal Utility of Deep Sequencing for HIV Drug Resistance Testing in the Age of Integrase Inhibitors

HIV drug resistance genotyping is a critical tool in the clinical management of HIV infections. Although resistance genotyping has traditionally been conducted using Sanger sequencing, next-generation sequencing (NGS) is emerging as a powerful tool due to its ability to detect low-frequency alleles....

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Detalles Bibliográficos
Autores principales: Dalmat, Ronit R., Makhsous, Negar, Pepper, Gregory G., Magaret, Amalia, Jerome, Keith R., Wald, Anna, Greninger, Alexander L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2018
Materias:
Virology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6258839/
https://www.ncbi.nlm.nih.gov/pubmed/30305383
http://dx.doi.org/10.1128/JCM.01443-18

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6258839/
https://www.ncbi.nlm.nih.gov/pubmed/30305383
http://dx.doi.org/10.1128/JCM.01443-18

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