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Alpha 1 Antitrypsin Gene Therapy Extends the Lifespan of Lupus-Prone Mice

Systemic lupus erythematosus (SLE) is a heterogeneous autoimmune disease characterized by high levels of pathogenic autoantibodies and tissue damage. Multiple studies showed that dendritic cell (DC) activation plays a critical role in SLE pathogenesis. Human alpha 1 antitrypsin (hAAT) is a serine pr...

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Detalles Bibliográficos
Autores principales:	Elshikha, Ahmed Samir, Yuan, Ye, Lu, Yuanqing, Chen, Mong-Jen, Abboud, Georges, Akbar, Mohammad Ahsanul, Plate, Henrike, Wolney, Hedwig, Hoffmann, Tanja, Tagari, Eleni, Zeumer, Leilani, Morel, Laurence, Song, Sihong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society of Gene & Cell Therapy 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6258868/ https://www.ncbi.nlm.nih.gov/pubmed/30547047 http://dx.doi.org/10.1016/j.omtm.2018.10.007

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