Cargando…

ABPS: An R Package for Calculating the Abnormal Blood Profile Score

The Abnormal Blood Profile Score (ABPS) is used to identify blood doping in sport. It combines seven hematological markers, including hemoglobin level, reticulocytes percent, and haematocrit level, using two different machine learning algorithms in order to create a single score that has a better ab...

Descripción completa

Detalles Bibliográficos
Autores principales: Schütz, Frédéric, Zollinger, Alix
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6258961/
https://www.ncbi.nlm.nih.gov/pubmed/30519191
http://dx.doi.org/10.3389/fphys.2018.01638
_version_ 1783374579113132032
author Schütz, Frédéric
Zollinger, Alix
author_facet Schütz, Frédéric
Zollinger, Alix
author_sort Schütz, Frédéric
collection PubMed
description The Abnormal Blood Profile Score (ABPS) is used to identify blood doping in sport. It combines seven hematological markers, including hemoglobin level, reticulocytes percent, and haematocrit level, using two different machine learning algorithms in order to create a single score that has a better ability to identify doping than each parameter taken alone. The resulting score allows the detection of several types of doping using a single score and is part of the current Athlete Biological Passport program managed by World Anti-Doping Agency (WADA). We describe ≪ ABPS ≫, an R package that allows the calculation of this score. This is the first software implementation calculating this score that is released publicly. The package also contains functions to calculate the OFF-score (another score used for detection of doping), as well as several test datasets. The package is useful for laboratories conducting anti-doping analyses and for researchers working on anti-doping research projects. In particular, it has been successfully used in projects estimating the prevalence of blood doping.
format Online
Article
Text
id pubmed-6258961
institution National Center for Biotechnology Information
language English
publishDate 2018
publisher Frontiers Media S.A.
record_format MEDLINE/PubMed
spelling pubmed-62589612018-12-05 ABPS: An R Package for Calculating the Abnormal Blood Profile Score Schütz, Frédéric Zollinger, Alix Front Physiol Physiology The Abnormal Blood Profile Score (ABPS) is used to identify blood doping in sport. It combines seven hematological markers, including hemoglobin level, reticulocytes percent, and haematocrit level, using two different machine learning algorithms in order to create a single score that has a better ability to identify doping than each parameter taken alone. The resulting score allows the detection of several types of doping using a single score and is part of the current Athlete Biological Passport program managed by World Anti-Doping Agency (WADA). We describe ≪ ABPS ≫, an R package that allows the calculation of this score. This is the first software implementation calculating this score that is released publicly. The package also contains functions to calculate the OFF-score (another score used for detection of doping), as well as several test datasets. The package is useful for laboratories conducting anti-doping analyses and for researchers working on anti-doping research projects. In particular, it has been successfully used in projects estimating the prevalence of blood doping. Frontiers Media S.A. 2018-11-21 /pmc/articles/PMC6258961/ /pubmed/30519191 http://dx.doi.org/10.3389/fphys.2018.01638 Text en Copyright © 2018 Schütz and Zollinger. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Physiology
Schütz, Frédéric
Zollinger, Alix
ABPS: An R Package for Calculating the Abnormal Blood Profile Score
title ABPS: An R Package for Calculating the Abnormal Blood Profile Score
title_full ABPS: An R Package for Calculating the Abnormal Blood Profile Score
title_fullStr ABPS: An R Package for Calculating the Abnormal Blood Profile Score
title_full_unstemmed ABPS: An R Package for Calculating the Abnormal Blood Profile Score
title_short ABPS: An R Package for Calculating the Abnormal Blood Profile Score
title_sort abps: an r package for calculating the abnormal blood profile score
topic Physiology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6258961/
https://www.ncbi.nlm.nih.gov/pubmed/30519191
http://dx.doi.org/10.3389/fphys.2018.01638
work_keys_str_mv AT schutzfrederic abpsanrpackageforcalculatingtheabnormalbloodprofilescore
AT zollingeralix abpsanrpackageforcalculatingtheabnormalbloodprofilescore