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Synthesis of 6-Amino-5-cyano-1,4-disubstituted-2(1H)-Pyrimidinones via Copper-(I)-catalyzed Alkyne-azide ‘Click Chemistry’ and Their Reactivity

In this paper we present the room temperature synthesis of a novel serie of 1,4-disubstituted-1,2,3-triazoles 4a-l by employing the (3 + 2) cycloaddition reaction of pyrimidinones containing alkyne functions with different model azides in the presence of copper sulphate and sodium ascorbate. To obta...

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Detalles Bibliográficos
Autores principales:	Najahi, Ennaji, Sudor, Jan, Chabchoub, Fakher, Nepveu, Françoise, Zribi, Fethi, Duval, Romain
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2010
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6259112/ https://www.ncbi.nlm.nih.gov/pubmed/21131903 http://dx.doi.org/10.3390/molecules15128841

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