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Synthesis and Biological Evaluation of Pyrazolo[1,5-a]-pyrimidine-containing (99m)Tc Nitrido Radiopharmaceuticals as Imaging Agents for Tumors
The compound 5-((2-aminoethylamino)methyl)-7-(4-bromoanilino)-3-cyano-pyrazolo[1,5-a]pyrimidine (ABCPP) was synthesized and conjugated with N-mercapto-acetylglycine (MAG), N-mercaptoacetylphenylalanine (MAF) and N-mercaptoacetylvaline (MAA), respectively. These three compounds were labeled successfu...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6259132/ https://www.ncbi.nlm.nih.gov/pubmed/21119567 http://dx.doi.org/10.3390/molecules15128723 |