Cargando…

Synthesis, Antimycobacterial, Antifungal and Photosynthesis-Inhibiting Activity of Chlorinated N-phenylpyrazine-2-carboxamides †

A series of sixteen pyrazinamide analogues with the -CONH- linker connecting the pyrazine and benzene rings was synthesized by the condensation of chlorides of substituted pyrazinecarboxylic acids with ring-substituted (chlorine) anilines. The prepared compounds were characterized and evaluated for...

Descripción completa

Detalles Bibliográficos
Autores principales:	Dolezal, Martin, Zitko, Jan, Osicka, Zdenek, Kunes, Jiri, Vejsova, Marcela, Buchta, Vladimir, Dohnal, Jiri, Jampilek, Josef, Kralova, Katarina
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2010
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6259134/ https://www.ncbi.nlm.nih.gov/pubmed/21116226 http://dx.doi.org/10.3390/molecules15128567

Ejemplares similares

Substituted N-Phenylpyrazine-2-carboxamides: Synthesis and Antimycobacterial Evaluation
por: Doležal, Martin, et al.
Publicado: (2009)

Synthesis, Antimycobacterial Activity and In Vitro Cytotoxicity of 5-Chloro-N-phenylpyrazine-2-carboxamides
por: Zitko, Jan, et al.
Publicado: (2013)

5-Alkylamino-N-phenylpyrazine-2-carboxamides: Design, Preparation, and Antimycobacterial Evaluation
por: Ambrożkiewicz, Weronika, et al.
Publicado: (2020)

Novel Pyrazine Analogs of Chalcones: Synthesis and Evaluation of Their Antifungal and Antimycobacterial Activity
por: Kucerova-Chlupacova, Marta, et al.
Publicado: (2015)

Rhodanineacetic Acid Derivatives as Potential Drugs: Preparation, Hydrophobic Properties and Antifungal Activity of (5-Arylalkylidene-4-oxo-2-thioxo-1,3-thiazolidin-3-yl)acetic Acids (†)
por: Dolezel, Jan, et al.
Publicado: (2009)

3-Substituted N-Benzylpyrazine-2-carboxamide Derivatives: Synthesis, Antimycobacterial and Antibacterial Evaluation
por: Semelková, Lucia, et al.
Publicado: (2017)

Synthesis and Characterization of (Z)-5-Arylmethylidene-rhodanines with Photosynthesis-Inhibiting Properties (†)
por: Opletalova, Veronika, et al.
Publicado: (2011)

Synthesis and Antifungal Screening of 2-{[1-(5-Alkyl/arylalkylpyrazin-2-yl)ethylidene]hydrazono}-1,3-thiazolidin-4-ones †
por: Opletalova, Veronika, et al.
Publicado: (2016)

Synthesis and Biological Evaluation of N-Alkyl-3-(alkylamino)-pyrazine-2-carboxamides
por: Semelkova, Lucia, et al.
Publicado: (2015)

New Potentially Active Pyrazinamide Derivatives Synthesized Under Microwave Conditions
por: Jandourek, Ondrej, et al.
Publicado: (2014)

Synthesis and Antimycobacterial and Photosynthesis-Inhibiting Evaluation of 2-[(E)-2-Substituted-ethenyl]-1,3-benzoxazoles
por: Imramovsky, Ales, et al.
Publicado: (2014)

Photosynthesis-Inhibiting Activity of N-(Disubstituted-phenyl)-3-hydroxynaphthalene-2-carboxamides †
por: Kos, Jiri, et al.
Publicado: (2021)

Investigating Biological Activity Spectrum for Novel Styrylquinazoline Analogues
por: Jampilek, Josef, et al.
Publicado: (2009)

N-Pyrazinoyl Substituted Amino Acids as Potential Antimycobacterial Agents—the Synthesis and Biological Evaluation of Enantiomers
por: Juhás, Martin, et al.
Publicado: (2020)

Design, Synthesis, Antimycobacterial Evaluation, and In Silico Studies of 3-(Phenylcarbamoyl)-pyrazine-2-carboxylic Acids
por: Semelková, Lucia, et al.
Publicado: (2017)

Derivatives of 3-Aminopyrazine-2-carboxamides: Synthesis, Antimicrobial Evaluation, and in Vitro Cytotoxicity
por: Bouz, Ghada, et al.
Publicado: (2019)

Substituted Amides of Pyrazine-2-carboxylic acids: Synthesis and Biological Activity.
por: Dolezal, Martin, et al.
Publicado: (2002)

Ring-substituted 4-Hydroxy-1H-quinolin-2-ones: Preparation and Biological Activity ‡
por: Jampilek, Josef, et al.
Publicado: (2009)

Design, Synthesis and Evaluation of N-pyrazinylbenzamides as Potential Antimycobacterial Agents
por: Zitko, Jan, et al.
Publicado: (2018)

Photosynthesis-Inhibiting Activity of 1-[(2-Chlorophenyl)carbamoyl]- and 1-[(2-Nitrophenyl)carbamoyl]naphthalen-2-yl Alkylcarbamates †
por: Gonec, Tomas, et al.
Publicado: (2017)

Investigating Spectrum of Biological Activity of 4- and 5-Chloro-2-hydroxy-N-[2-(arylamino)-1-alkyl-2-oxoethyl]benzamides
por: Imramovsky, Ales, et al.
Publicado: (2011)

N-Alkoxyphenylhydroxynaphthalenecarboxamides and Their Antimycobacterial Activity
por: Gonec, Tomas, et al.
Publicado: (2016)

Adenosine-Mimicking Derivatives of 3-Aminopyrazine-2-Carboxamide: Towards Inhibitors of Prolyl-tRNA Synthetase with Antimycobacterial Activity
por: Pallabothula, Vinod Sukanth Kumar, et al.
Publicado: (2022)

Potential of Nanomaterial Applications in Dietary Supplements and Foods for Special Medical Purposes
por: Jampilek, Josef, et al.
Publicado: (2019)

Investigating the Spectrum of Biological Activity of Substituted Quinoline-2-Carboxamides and Their Isosteres (†)
por: Gonec, Tomas, et al.
Publicado: (2012)

Novel Halogenated Pyrazine-Based Chalcones as Potential Antimicrobial Drugs †
por: Kucerova-Chlupacova, Marta, et al.
Publicado: (2016)

Substituted N-Benzylpyrazine-2-carboxamides: Synthesis and Biological Evaluation (†)
por: Servusová, Barbora, et al.
Publicado: (2012)

Investigation of the Biological Properties of (Hetero)Aromatic Thiosemicarbazones
por: Serda, Maciej, et al.
Publicado: (2012)

Semisynthetic Derivatives of Selected Amaryllidaceae Alkaloids as a New Class of Antimycobacterial Agents
por: Maafi, Negar, et al.
Publicado: (2021)

5-Bromo-N (3)-phenylpyrazine-2,3-diamine
por: Zhu, Xiaohui
Publicado: (2009)

Alkaloids of Dicranostigma franchetianum (Papaveraceae) and Berberine Derivatives as a New Class of Antimycobacterial Agents
por: Wijaya, Viriyanata, et al.
Publicado: (2022)

N-Substituted 5-Amino-6-methylpyrazine-2,3-dicarbonitriles: Microwave-Assisted Synthesis and Biological Properties
por: Jandourek, Ondrej, et al.
Publicado: (2014)

Antimycobacterial and Photosynthetic Electron Transport Inhibiting Activity of Ring-Substituted 4-Arylamino-7-Chloroquinolinium Chlorides
por: Otevrel, Jan, et al.
Publicado: (2013)

Investigating the Activity Spectrum for Ring-Substituted 8-Hydroxyquinolines
por: Musiol, Robert, et al.
Publicado: (2010)

In Vitro Permeation of Micronized and Nanonized Alaptide from Semisolid Formulations
por: Opatrilova, Radka, et al.
Publicado: (2013)

Primary Investigation of the Preparation of Nanoparticles by Precipitation
por: Vaculikova, Eliska, et al.
Publicado: (2012)

Preparation of Candesartan and Atorvastatin Nanoparticles by Solvent Evaporation (†)
por: Vaculikova, Eliska, et al.
Publicado: (2012)

Synthesis, Biological Evaluation, and In Silico Modeling of N-Substituted Quinoxaline-2-Carboxamides
por: Bouz, Ghada, et al.
Publicado: (2021)

In Silico Studies of Quinoxaline-2-Carboxamide 1,4-di-N-Oxide Derivatives as Antimycobacterial Agents
por: Radwan, Awwad A., et al.
Publicado: (2014)

Potential of Nanonutraceuticals in Increasing Immunity
por: Jampilek, Josef, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_lvk9o3agj68ptg1lp3edr5baap