Catalytic Asymmetric Synthesis of Both Enantiomers of 4‑Substituted 1,4-Dihydropyridines with the Use of Bifunctional Thiourea-Ammonium Salts Bearing Different Counterions

Organoammonium salts composed of a Brønsted acid and an anilinothiourea promoted the Michael addition of β-keto esters and α,β-unsaturated aldehydes in the presence of primary amines to give functionalized 1,4-dihydropyridines enantioselectively. With the use of the different Brønsted acids such as...

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Detalles Bibliográficos
Autores principales: Yoshida, Kohzo, Inokuma, Tsubasa, Takasu, Kiyosei, Takemoto, Yoshiji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6259149/
https://www.ncbi.nlm.nih.gov/pubmed/21079568
http://dx.doi.org/10.3390/molecules15118305

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6259149/
https://www.ncbi.nlm.nih.gov/pubmed/21079568
http://dx.doi.org/10.3390/molecules15118305

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