Sonogashira Reaction of Aryl and Heteroaryl Halides with Terminal Alkynes Catalyzed by a Highly Efficient and Recyclable Nanosized MCM-41 Anchored Palladium Bipyridyl Complex

A heterogeneous catalyst, nanosized MCM-41-Pd, was used to catalyze the Sonogashira coupling of aryl and heteroaryl halides with terminal alkynes in the presence of CuI and triphenylphosphine. The coupling products were obtained in high yields using low Pd loadings to 0.01 mol%, and the nanosized MC...

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Autores principales: Lin, Bo-Nan, Huang, Shao-Hsien, Wu, Wei-Yi, Mou, Chung-Yuan, Tsai, Fu-Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6259169/
https://www.ncbi.nlm.nih.gov/pubmed/21150831
http://dx.doi.org/10.3390/molecules15129157
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author Lin, Bo-Nan
Huang, Shao-Hsien
Wu, Wei-Yi
Mou, Chung-Yuan
Tsai, Fu-Yu
author_facet Lin, Bo-Nan
Huang, Shao-Hsien
Wu, Wei-Yi
Mou, Chung-Yuan
Tsai, Fu-Yu
author_sort Lin, Bo-Nan
collection PubMed
description A heterogeneous catalyst, nanosized MCM-41-Pd, was used to catalyze the Sonogashira coupling of aryl and heteroaryl halides with terminal alkynes in the presence of CuI and triphenylphosphine. The coupling products were obtained in high yields using low Pd loadings to 0.01 mol%, and the nanosized MCM-41-Pd catalyst was recovered by centrifugation of the reaction solution and re-used in further runs without significant loss of reactivity.
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spelling pubmed-62591692018-12-06 Sonogashira Reaction of Aryl and Heteroaryl Halides with Terminal Alkynes Catalyzed by a Highly Efficient and Recyclable Nanosized MCM-41 Anchored Palladium Bipyridyl Complex Lin, Bo-Nan Huang, Shao-Hsien Wu, Wei-Yi Mou, Chung-Yuan Tsai, Fu-Yu Molecules Article A heterogeneous catalyst, nanosized MCM-41-Pd, was used to catalyze the Sonogashira coupling of aryl and heteroaryl halides with terminal alkynes in the presence of CuI and triphenylphosphine. The coupling products were obtained in high yields using low Pd loadings to 0.01 mol%, and the nanosized MCM-41-Pd catalyst was recovered by centrifugation of the reaction solution and re-used in further runs without significant loss of reactivity. MDPI 2010-12-10 /pmc/articles/PMC6259169/ /pubmed/21150831 http://dx.doi.org/10.3390/molecules15129157 Text en © 2010 by the authors; http://creativecommons.org/licenses/by/3.0/ licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Article
Lin, Bo-Nan
Huang, Shao-Hsien
Wu, Wei-Yi
Mou, Chung-Yuan
Tsai, Fu-Yu
Sonogashira Reaction of Aryl and Heteroaryl Halides with Terminal Alkynes Catalyzed by a Highly Efficient and Recyclable Nanosized MCM-41 Anchored Palladium Bipyridyl Complex
title Sonogashira Reaction of Aryl and Heteroaryl Halides with Terminal Alkynes Catalyzed by a Highly Efficient and Recyclable Nanosized MCM-41 Anchored Palladium Bipyridyl Complex
title_full Sonogashira Reaction of Aryl and Heteroaryl Halides with Terminal Alkynes Catalyzed by a Highly Efficient and Recyclable Nanosized MCM-41 Anchored Palladium Bipyridyl Complex
title_fullStr Sonogashira Reaction of Aryl and Heteroaryl Halides with Terminal Alkynes Catalyzed by a Highly Efficient and Recyclable Nanosized MCM-41 Anchored Palladium Bipyridyl Complex
title_full_unstemmed Sonogashira Reaction of Aryl and Heteroaryl Halides with Terminal Alkynes Catalyzed by a Highly Efficient and Recyclable Nanosized MCM-41 Anchored Palladium Bipyridyl Complex
title_short Sonogashira Reaction of Aryl and Heteroaryl Halides with Terminal Alkynes Catalyzed by a Highly Efficient and Recyclable Nanosized MCM-41 Anchored Palladium Bipyridyl Complex
title_sort sonogashira reaction of aryl and heteroaryl halides with terminal alkynes catalyzed by a highly efficient and recyclable nanosized mcm-41 anchored palladium bipyridyl complex
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6259169/
https://www.ncbi.nlm.nih.gov/pubmed/21150831
http://dx.doi.org/10.3390/molecules15129157
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