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Synthesis and Tumor Cytotoxicity of Novel Amide Derivatives of β-Hederin

Thirteen novel triterpenoid saponins, designed as amide derivatives of the natural cytotoxic saponin β-hederin, were synthesized by a stepwise glycosylation strategy. The in vitro cytotoxic activity of these compounds was evaluated against five different tumor cell lines. Most of the evaluated compo...

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Detalles Bibliográficos
Autores principales:	Liu, Yang, Lu, Wen-Xiang, Yan, Mao-Cai, Yu, Yang, Ikejima, Takashi, Cheng, Mao-Sheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2010
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6259211/ https://www.ncbi.nlm.nih.gov/pubmed/21060295 http://dx.doi.org/10.3390/molecules15117871

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