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The Pharmacokinetics of Raloxifene and Its Interaction with Apigenin in Rat

Purpose: Raloxifene is a selective estrogen receptor modulator which is structurally similar to tamoxifen. As flavonoids can interact with raloxifene in vitro, we evaluated the in vivo pharmacokinetics of raloxifene in rats when co-administered with apigenin. Methods: The pharmacokinetics of raloxif...

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Detalles Bibliográficos
Autores principales: Chen, Yan, Jia, Xiaobin, Chen, Jian, Wang, Jinyan, Hu, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6259217/
https://www.ncbi.nlm.nih.gov/pubmed/21088662
http://dx.doi.org/10.3390/molecules15118478