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The Pharmacokinetics of Raloxifene and Its Interaction with Apigenin in Rat
Purpose: Raloxifene is a selective estrogen receptor modulator which is structurally similar to tamoxifen. As flavonoids can interact with raloxifene in vitro, we evaluated the in vivo pharmacokinetics of raloxifene in rats when co-administered with apigenin. Methods: The pharmacokinetics of raloxif...
Autores principales: | Chen, Yan, Jia, Xiaobin, Chen, Jian, Wang, Jinyan, Hu, Ming |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6259217/ https://www.ncbi.nlm.nih.gov/pubmed/21088662 http://dx.doi.org/10.3390/molecules15118478 |
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