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A Novel Benzo[f][1,7]Naphthyridine Produced by Streptomyces Albogriseolus from Mangrove Sediments
Mangrove Streptomyces represent a rich source of novel bioactive compounds in medicinal research. A novel alkaloid, named 1-N-methyl-3-methylamino-[N-butanoic acid-3′-(9′-methyl-8′-propen-7′-one)-amide]-benzo[f][1,7]naphthyridine-2-one (1) was isolated from Streptomyces albogriseolus originating fro...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6259242/ https://www.ncbi.nlm.nih.gov/pubmed/21160454 http://dx.doi.org/10.3390/molecules15129298 |
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author | Li, Xiao-Ling Xu, Min-Juan Zhao, Yi-Lei Xu, Jun |
author_facet | Li, Xiao-Ling Xu, Min-Juan Zhao, Yi-Lei Xu, Jun |
author_sort | Li, Xiao-Ling |
collection | PubMed |
description | Mangrove Streptomyces represent a rich source of novel bioactive compounds in medicinal research. A novel alkaloid, named 1-N-methyl-3-methylamino-[N-butanoic acid-3′-(9′-methyl-8′-propen-7′-one)-amide]-benzo[f][1,7]naphthyridine-2-one (1) was isolated from Streptomyces albogriseolus originating from mangrove sediments. The structure of compound 1 was elucidated by extensive spectroscopic data analyses and verified by the (13)C-NMR calculation at the B3LYP/6-311+G(2d,p) level of theory. |
format | Online Article Text |
id | pubmed-6259242 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2010 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-62592422018-12-06 A Novel Benzo[f][1,7]Naphthyridine Produced by Streptomyces Albogriseolus from Mangrove Sediments Li, Xiao-Ling Xu, Min-Juan Zhao, Yi-Lei Xu, Jun Molecules Article Mangrove Streptomyces represent a rich source of novel bioactive compounds in medicinal research. A novel alkaloid, named 1-N-methyl-3-methylamino-[N-butanoic acid-3′-(9′-methyl-8′-propen-7′-one)-amide]-benzo[f][1,7]naphthyridine-2-one (1) was isolated from Streptomyces albogriseolus originating from mangrove sediments. The structure of compound 1 was elucidated by extensive spectroscopic data analyses and verified by the (13)C-NMR calculation at the B3LYP/6-311+G(2d,p) level of theory. MDPI 2010-12-15 /pmc/articles/PMC6259242/ /pubmed/21160454 http://dx.doi.org/10.3390/molecules15129298 Text en © 2010 by the authors; http://creativecommons.org/licenses/by/3.0/ licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/). |
spellingShingle | Article Li, Xiao-Ling Xu, Min-Juan Zhao, Yi-Lei Xu, Jun A Novel Benzo[f][1,7]Naphthyridine Produced by Streptomyces Albogriseolus from Mangrove Sediments |
title | A Novel Benzo[f][1,7]Naphthyridine Produced by Streptomyces Albogriseolus from Mangrove Sediments |
title_full | A Novel Benzo[f][1,7]Naphthyridine Produced by Streptomyces Albogriseolus from Mangrove Sediments |
title_fullStr | A Novel Benzo[f][1,7]Naphthyridine Produced by Streptomyces Albogriseolus from Mangrove Sediments |
title_full_unstemmed | A Novel Benzo[f][1,7]Naphthyridine Produced by Streptomyces Albogriseolus from Mangrove Sediments |
title_short | A Novel Benzo[f][1,7]Naphthyridine Produced by Streptomyces Albogriseolus from Mangrove Sediments |
title_sort | novel benzo[f][1,7]naphthyridine produced by streptomyces albogriseolus from mangrove sediments |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6259242/ https://www.ncbi.nlm.nih.gov/pubmed/21160454 http://dx.doi.org/10.3390/molecules15129298 |
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