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Efficient Microwave-Assisted Synthesis of 5-Deazaflavine Derivatives

A series of pyrimido[4,5-b]quinolines (5-deazaflavines), were synthesized by microwave assisted intramolecular cyclization. The N(4)-substituted-2,4-diamino-6-chloro-pyrimidine-5-carbaldehydes, were prepared by selective monoamination of 2-amino-4,6-dichloropyrimidine-5-carbaldehyde with aliphatic a...

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Detalles Bibliográficos
Autores principales: Trilleras, Jorge, López, Luis Gabriel, Pacheco, Dency José, Quiroga, Jairo, Nogueras, Manuel, de la Torre, José M., Cobo, Justo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6259259/
https://www.ncbi.nlm.nih.gov/pubmed/20966872
http://dx.doi.org/10.3390/molecules15107227