Functionalized 4-Hydroxy Coumarins: Novel Synthesis, Crystal Structure and DFT Calculations

A novel short-step methodology for the synthesis in good yields of functionalized coumarins has been developed starting from an activated precursor, the N-hydroxysuccinimide ester of O-acetylsalicylic acid. The procedure is based on a tandem C-acylation-cyclization process under mild reaction condit...

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Detalles Bibliográficos
Autores principales: Stefanou, Valentina, Matiadis, Dimitris, Melagraki, Georgia, Afantitis, Antreas, Athanasellis, Giorgos, Igglessi-Markopoulou, Olga, McKee, Vickie, Markopoulos, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6259271/
https://www.ncbi.nlm.nih.gov/pubmed/21217604
http://dx.doi.org/10.3390/molecules16010384

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6259271/
https://www.ncbi.nlm.nih.gov/pubmed/21217604
http://dx.doi.org/10.3390/molecules16010384

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