[2+2+2] Cycloaddition Reactions of Macrocyclic Systems Catalyzed by Transition Metals. A Review

Polyalkyne and enediyne azamacrocycles are prepared from arenesulfonamides and various alkyne and alkene derivatives either under basic or neutral conditions. The new family of macrocyclic substrates is tested in the [2+2+2] cycloaddition reaction. Several catalysts are used for the cycloisomerizati...

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Detalles Bibliográficos
Autores principales: Pla-Quintana, Anna, Roglans, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2010
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6259275/
https://www.ncbi.nlm.nih.gov/pubmed/21160451
http://dx.doi.org/10.3390/molecules15129230
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author Pla-Quintana, Anna
Roglans, Anna
author_facet Pla-Quintana, Anna
Roglans, Anna
author_sort Pla-Quintana, Anna
collection PubMed
description Polyalkyne and enediyne azamacrocycles are prepared from arenesulfonamides and various alkyne and alkene derivatives either under basic or neutral conditions. The new family of macrocyclic substrates is tested in the [2+2+2] cycloaddition reaction. Several catalysts are used for the cycloisomerization reaction, and their enantioinduction is evaluated as appropriate. The effect of the structural features of the macrocycles, namely the ring size, substituents in precise positions and the number and type of unsaturations, on the [2+2+2] cycloaddition reaction has also been studied.
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spelling pubmed-62592752018-12-06 [2+2+2] Cycloaddition Reactions of Macrocyclic Systems Catalyzed by Transition Metals. A Review Pla-Quintana, Anna Roglans, Anna Molecules Review Polyalkyne and enediyne azamacrocycles are prepared from arenesulfonamides and various alkyne and alkene derivatives either under basic or neutral conditions. The new family of macrocyclic substrates is tested in the [2+2+2] cycloaddition reaction. Several catalysts are used for the cycloisomerization reaction, and their enantioinduction is evaluated as appropriate. The effect of the structural features of the macrocycles, namely the ring size, substituents in precise positions and the number and type of unsaturations, on the [2+2+2] cycloaddition reaction has also been studied. MDPI 2010-12-15 /pmc/articles/PMC6259275/ /pubmed/21160451 http://dx.doi.org/10.3390/molecules15129230 Text en © 2010 by the authors; http://creativecommons.org/licenses/by/3.0/ licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Review
Pla-Quintana, Anna
Roglans, Anna
[2+2+2] Cycloaddition Reactions of Macrocyclic Systems Catalyzed by Transition Metals. A Review
title [2+2+2] Cycloaddition Reactions of Macrocyclic Systems Catalyzed by Transition Metals. A Review
title_full [2+2+2] Cycloaddition Reactions of Macrocyclic Systems Catalyzed by Transition Metals. A Review
title_fullStr [2+2+2] Cycloaddition Reactions of Macrocyclic Systems Catalyzed by Transition Metals. A Review
title_full_unstemmed [2+2+2] Cycloaddition Reactions of Macrocyclic Systems Catalyzed by Transition Metals. A Review
title_short [2+2+2] Cycloaddition Reactions of Macrocyclic Systems Catalyzed by Transition Metals. A Review
title_sort [2+2+2] cycloaddition reactions of macrocyclic systems catalyzed by transition metals. a review
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6259275/
https://www.ncbi.nlm.nih.gov/pubmed/21160451
http://dx.doi.org/10.3390/molecules15129230
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AT roglansanna 222cycloadditionreactionsofmacrocyclicsystemscatalyzedbytransitionmetalsareview

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