Cargando…

Molecular Modeling Studies on 11H-Dibenz[b,e]azepine and Dibenz[b,f][1,4]oxazepine Derivatives as Potent Agonists of the Human TRPA1 Receptor

A computational strategy based on comparative molecular fields analysis (CoMFA) and comparative molecular similarity indices analysis (CoMSIA) was performed on a series of the 11H-dibenz[b,e]azepine and dibenz[b,f][1,4]oxazepine derivatives as potent agonists of the human TRPA1 receptor. The CoMFA a...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ai, Yong, Song, Fa-Jun, Wang, Shao-Teng, Sun, Qiang, Sun, Ping-Hua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2010
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6259276/ https://www.ncbi.nlm.nih.gov/pubmed/21169885 http://dx.doi.org/10.3390/molecules15129364

Ejemplares similares

Intramolecular asymmetric reductive amination: synthesis of enantioenriched dibenz[c,e]azepines
por: Yang, Tao, et al.
Publicado: (2018)

Effect of dibenz(b,f)-1,4-oxazepine aerosol on the breathing pattern and respiratory variables by continuous recording and analysis in unanaesthetised mice
por: Vijayaraghavan, Rajagopalan, et al.
Publicado: (2020)

6,11-Dihydrodibenz[b,e]oxepin-11-one
por: Jasinski, Jerry P., et al.
Publicado: (2009)

A New Dibenz[b, e]oxepine Derivative, 1-Hydroxy-10-methoxy-dibenz[b, e]oxepin-6,11-dione, from a Marine-Derived Fungus, Beauveria bassiana TPU942
por: Yamazaki, Hiroyuki, et al.
Publicado: (2012)

New Short Strategy for the Synthesis of the Dibenz[b,f]oxepin Scaffold
por: Moreno, David R. R., et al.
Publicado: (2013)

1,3-Dibenzyloxy-5-(bromomethyl)benzene
por: Zhu, Peihua, et al.
Publicado: (2009)

4,4′-(Propane-1,3-diyldioxy)dibenzaldehyde
por: Ali, Qamar, et al.
Publicado: (2010)

2,2′-[Ethane-1,2-diylbis(oxy)]dibenzaldehyde
por: Akkurt, Mehmet, et al.
Publicado: (2013)

Butterfly-Shaped Dibenz[a,j]anthracenes: Synthesis and Photophysical Properties
por: Wu, Yan-Ying, et al.
Publicado: (2023)

3-(2,4-Dimethoxyanilino)-8-methoxydibenz[b,e]oxepin-11(6H)-one
por: Baur, Benjamin, et al.
Publicado: (2011)

Stereoselective metabolism of dibenz(a,h)anthracene to trans-dihydrodiols and their activation to bacterial mutagens.
por: Platt, K L, et al.
Publicado: (1990)

2,2′-(Heptane-1,7-diyl)dibenzimidazolium chloride nitrate monohydrate
por: Zeng, Jin-Ping, et al.
Publicado: (2009)

2,2′-(Decane-1,10-diyl)dibenzimidazolium dichloride trihydrate
por: Yi, Jun-Ming, et al.
Publicado: (2008)

1-(3-Benzyl-4,6-dibenzyloxy-2-hydroxyphenyl)ethanone
por: Hill, Tania N., et al.
Publicado: (2012)

Crystal structure of 1,13,14-triazadibenz[a,j]anthracene 1,1,2,2-tetrachloroethane monosolvate
por: Koizumi, Take-aki, et al.
Publicado: (2015)

In Silico and In Vitro Experimental Studies of New Dibenz[b,e]oxepin-11(6H)one O-(arylcarbamoyl)-oximes Designed as Potential Antimicrobial Agents
por: Vlad, Ilinca Margareta, et al.
Publicado: (2020)

2,2′-(Iminodimethylene)dibenzimidazolium bis(perchlorate) methanol solvate
por: Zhou, Chun-Shan, et al.
Publicado: (2008)

6-(1-Methylethyl)-12-phenyl-5,6,7,12-tetrahydrodibenz[c,f][1,5]azasilocine
por: Goto, Kei, et al.
Publicado: (2009)

11H-Dibenzo[b,e]azepine-6-carbonitrile
por: Fan, Guo-Dong, et al.
Publicado: (2008)

The effects of different social conditions on breast cancer induction in three genetic types of mice by dibenz[a,h]anthracene and a comparison with breast carcinogenesis by 3-methylcholanthrene.
por: Marchant, J.
Publicado: (1967)

(3aR*,5R*)-5-(4-Chlorophenyl)-1,2,3,3a-tetrahydrobenzo[e]pyrrolo[2,1-b][1,3]oxazepin-10(5H)-one
por: Jin, Yun-Zhou, et al.
Publicado: (2011)

Synthesis, Spectroscopic, X-ray Diffraction and DFT Studies of Novel Benzimidazole Fused-1,4-Oxazepines
por: Almansour, Abdulrahman I., et al.
Publicado: (2016)

{Bis[2-(diphenylphosphanyl)phenyl] ether-κ(2) P,P′}(1,1′-dibenzyl-1H,1′H-4,4′bi-1,2,3-triazole-κ(2) N(3),N (3′))copper(I) hexafluoridophosphate dichloromethane hemisolvate
por: Monkowius, Uwe, et al.
Publicado: (2007)

Facile Synthesis for Benzo-1,4-Oxazepine Derivatives by Tandem Transformation of C-N Coupling/C-H Carbonylation
por: Zhao, Xiaojia, et al.
Publicado: (2016)

TRPA1 Agonist Cinnamaldehyde Decreases Adipogenesis in 3T3-L1 Cells More Potently than the Non-agonist Structural Analog Cinnamyl Isobutyrate
por: Hoi, Julia K., et al.
Publicado: (2020)

Potent Activation of Human but Not Mouse TRPA1 by JT010
por: Matsubara, Masaki, et al.
Publicado: (2022)

The Agonist Action of Alkylphenols on TRPA1 Relates to Their Effects on Membrane Lipid Order: Implications for TRPA1-Mediated Chemosensation
por: Startek, Justyna B., et al.
Publicado: (2021)

5-(Prop-2-ynyl)-5H-dibenzo[b,f]azepine
por: Yousuf, S., et al.
Publicado: (2012)

Anti-cancer activity of novel dibenzo[b,f]azepine tethered isoxazoline derivatives
por: Sadashiva, Maralinganadoddi Panchegowda, et al.
Publicado: (2012)

Asymmetric synthesis of dibenzo[b,d]azepines by Cu-catalyzed reductive or borylative cyclization
por: Rodríguez-Salamanca, Patricia, et al.
Publicado: (2021)

Substrate Switchable Pathway for Selective Construction of Bridged Dibenzo[b,f][1,5]diazocines and Bridged Spiromethanodibenzo[b,e]azepines
por: Pramanik, Sayan, et al.
Publicado: (2023)

Dihydrobenz[e][1,4]oxazepin-2(3H)-ones, a new anthelmintic chemotype immobilising whipworm and reducing infectivity in vivo
por: Partridge, Frederick A., et al.
Publicado: (2017)

Stereodivergent access to all four stereoisomers of chiral tetrahydrobenzo[f][1,4]oxazepines, through highly diastereoselective multicomponent Ugi–Joullié reaction
por: Pinna, Alessandro, et al.
Publicado: (2020)

5-(Prop-2-yn-1-yl)-5H-dibenzo[b,f]azepine: orthorhombic polymorph
por: Abdoh, M. M. M., et al.
Publicado: (2012)

5-Methyl-1,2,3,3a-tetrahydrobenzo[e]pyrrolo[2,1-b][1,3]oxazepin-10(5H)-one
por: Jin, Yun-Zhou, et al.
Publicado: (2011)

5-[(4-Benzyl-1H-1,2,3-triazol-1-yl)methyl]-5H-dibenzo[b,f]azepine
por: Manjunath, B. C., et al.
Publicado: (2013)

5-[(1-Benzyl-1H-1,2,3-triazol-4-yl)methyl]-5H-dibenzo[b,f]azepine
por: Manjunath, B. C., et al.
Publicado: (2013)

Stereochemistry of N-Acyl-5H-dibenzo[b,d]azepin-7(6H)-ones
por: Chiba, Arisa, et al.
Publicado: (2023)

New natural agonists of the transient receptor potential Ankyrin 1 (TRPA1) channel
por: Legrand, Coline, et al.
Publicado: (2020)

Adamantyl Analogues of Paracetamol as Potent Analgesic Drugs via Inhibition of TRPA1
por: Fresno, Nieves, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_dln6mri9agg43m4e7lhli4rqcf