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Vitamin D Levels: Do We Need to Assess Only in Disease?

BACKGROUND: Vitamin D is conventionally known as sunshine vitamin and is synthesized endogenously in sunlight. Vitamin D is known to be a key regulator of bone metabolism, the function of genes, and essential for the development of the whole body. Deficiency of Vitamin D is now become a major worldw...

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Autores principales: Jamwal, Sunil, Gupta, Kapil, Sidhu, Tanvir Kaur
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6259298/
https://www.ncbi.nlm.nih.gov/pubmed/30598909
http://dx.doi.org/10.4103/ijabmr.IJABMR_105_18
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author Jamwal, Sunil
Gupta, Kapil
Sidhu, Tanvir Kaur
author_facet Jamwal, Sunil
Gupta, Kapil
Sidhu, Tanvir Kaur
author_sort Jamwal, Sunil
collection PubMed
description BACKGROUND: Vitamin D is conventionally known as sunshine vitamin and is synthesized endogenously in sunlight. Vitamin D is known to be a key regulator of bone metabolism, the function of genes, and essential for the development of the whole body. Deficiency of Vitamin D is now become a major worldwide epidemic health problem. AIM: The present study was conducted with the objective of determining the prevalence of Vitamin D deficiency (VDD) in urban population of a district in south Punjab, across various characteristics of population such as gender, age, and socioeconomic status. MATERIALS AND METHODS: A cross-sectional population survey was conducted in the urban population of the district. A total of 120 healthy volunteers of either sex participated and their 25-hydroxy Vitamin D concentrations in serum samples were estimated using ELISA. The participants were divided into three categories as follows: Vitamin D deficient, insufficient, or sufficient, on the basis of normal standardized serum levels of Vitamin D <20, 20–30, and >30 ng/ml, respectively. RESULTS: Of 120 healthy individuals, 95% of the study participants had VDD or insufficiency and only 5% had adequate Vitamin D levels. In each age group, females showed lower Vitamin D levels as compared to males. Furthermore, high body mass index value was associated with low Vitamin D. Upper-class individuals also showed low levels of Vitamin D as compared to other socioeconomic classes' individuals. CONCLUSIONS: Overall, high prevalence of VDD among the apparently healthy urban population of the district was observed and gives an alarming sign about continuously increasing prevalence of hypovitaminosis D among healthy population.
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spelling pubmed-62592982018-12-31 Vitamin D Levels: Do We Need to Assess Only in Disease? Jamwal, Sunil Gupta, Kapil Sidhu, Tanvir Kaur Int J Appl Basic Med Res Original Article BACKGROUND: Vitamin D is conventionally known as sunshine vitamin and is synthesized endogenously in sunlight. Vitamin D is known to be a key regulator of bone metabolism, the function of genes, and essential for the development of the whole body. Deficiency of Vitamin D is now become a major worldwide epidemic health problem. AIM: The present study was conducted with the objective of determining the prevalence of Vitamin D deficiency (VDD) in urban population of a district in south Punjab, across various characteristics of population such as gender, age, and socioeconomic status. MATERIALS AND METHODS: A cross-sectional population survey was conducted in the urban population of the district. A total of 120 healthy volunteers of either sex participated and their 25-hydroxy Vitamin D concentrations in serum samples were estimated using ELISA. The participants were divided into three categories as follows: Vitamin D deficient, insufficient, or sufficient, on the basis of normal standardized serum levels of Vitamin D <20, 20–30, and >30 ng/ml, respectively. RESULTS: Of 120 healthy individuals, 95% of the study participants had VDD or insufficiency and only 5% had adequate Vitamin D levels. In each age group, females showed lower Vitamin D levels as compared to males. Furthermore, high body mass index value was associated with low Vitamin D. Upper-class individuals also showed low levels of Vitamin D as compared to other socioeconomic classes' individuals. CONCLUSIONS: Overall, high prevalence of VDD among the apparently healthy urban population of the district was observed and gives an alarming sign about continuously increasing prevalence of hypovitaminosis D among healthy population. Medknow Publications & Media Pvt Ltd 2018 /pmc/articles/PMC6259298/ /pubmed/30598909 http://dx.doi.org/10.4103/ijabmr.IJABMR_105_18 Text en Copyright: © 2018 International Journal of Applied and Basic Medical Research http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Original Article
Jamwal, Sunil
Gupta, Kapil
Sidhu, Tanvir Kaur
Vitamin D Levels: Do We Need to Assess Only in Disease?
title Vitamin D Levels: Do We Need to Assess Only in Disease?
title_full Vitamin D Levels: Do We Need to Assess Only in Disease?
title_fullStr Vitamin D Levels: Do We Need to Assess Only in Disease?
title_full_unstemmed Vitamin D Levels: Do We Need to Assess Only in Disease?
title_short Vitamin D Levels: Do We Need to Assess Only in Disease?
title_sort vitamin d levels: do we need to assess only in disease?
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6259298/
https://www.ncbi.nlm.nih.gov/pubmed/30598909
http://dx.doi.org/10.4103/ijabmr.IJABMR_105_18
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