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Dermal Lymphatic Invasion: A Rare Feature in Benign Intradermal Nevus

The present case describes classical intradermal nevus with intralymphatic nevus cell emboli. A 13-year-old boy presented with black colored macule on the shin 1 cm in diameter which was gradually increasing in size. Histopathology of the lesion was typical of an intradermal melanocytic nevus. The m...

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Autores principales: Sood, Neelam, Mukherjee, Moushmi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6259301/
https://www.ncbi.nlm.nih.gov/pubmed/30598914
http://dx.doi.org/10.4103/ijabmr.IJABMR_397_17
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author Sood, Neelam
Mukherjee, Moushmi
author_facet Sood, Neelam
Mukherjee, Moushmi
author_sort Sood, Neelam
collection PubMed
description The present case describes classical intradermal nevus with intralymphatic nevus cell emboli. A 13-year-old boy presented with black colored macule on the shin 1 cm in diameter which was gradually increasing in size. Histopathology of the lesion was typical of an intradermal melanocytic nevus. The most notable feature of this case, however, was an occasional aggregate of nevus cells within a lymphatic vessel of the upper dermis. The nevus cells within lymphatic lumen had morphological features of type A nevus cells. The cells were roundtocuboidal, exhibited abundant cytoplasm with welldefined cell borders and formed nests. These nevus cell aggregates were surrounded by flattened endothelial cells. Due to its rarity, a lymphatic nevus cell embolus creates diagnostic issues for pathologists. This observation must not be interpreted as evidence of malignancy but significant as a rare histological feature. In other words, the nevus cells might have been transported through the lymphatic vessels as a “benign metastasis.”
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spelling pubmed-62593012018-12-31 Dermal Lymphatic Invasion: A Rare Feature in Benign Intradermal Nevus Sood, Neelam Mukherjee, Moushmi Int J Appl Basic Med Res Case Report The present case describes classical intradermal nevus with intralymphatic nevus cell emboli. A 13-year-old boy presented with black colored macule on the shin 1 cm in diameter which was gradually increasing in size. Histopathology of the lesion was typical of an intradermal melanocytic nevus. The most notable feature of this case, however, was an occasional aggregate of nevus cells within a lymphatic vessel of the upper dermis. The nevus cells within lymphatic lumen had morphological features of type A nevus cells. The cells were roundtocuboidal, exhibited abundant cytoplasm with welldefined cell borders and formed nests. These nevus cell aggregates were surrounded by flattened endothelial cells. Due to its rarity, a lymphatic nevus cell embolus creates diagnostic issues for pathologists. This observation must not be interpreted as evidence of malignancy but significant as a rare histological feature. In other words, the nevus cells might have been transported through the lymphatic vessels as a “benign metastasis.” Medknow Publications & Media Pvt Ltd 2018 /pmc/articles/PMC6259301/ /pubmed/30598914 http://dx.doi.org/10.4103/ijabmr.IJABMR_397_17 Text en Copyright: © 2018 International Journal of Applied and Basic Medical Research http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Case Report
Sood, Neelam
Mukherjee, Moushmi
Dermal Lymphatic Invasion: A Rare Feature in Benign Intradermal Nevus
title Dermal Lymphatic Invasion: A Rare Feature in Benign Intradermal Nevus
title_full Dermal Lymphatic Invasion: A Rare Feature in Benign Intradermal Nevus
title_fullStr Dermal Lymphatic Invasion: A Rare Feature in Benign Intradermal Nevus
title_full_unstemmed Dermal Lymphatic Invasion: A Rare Feature in Benign Intradermal Nevus
title_short Dermal Lymphatic Invasion: A Rare Feature in Benign Intradermal Nevus
title_sort dermal lymphatic invasion: a rare feature in benign intradermal nevus
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6259301/
https://www.ncbi.nlm.nih.gov/pubmed/30598914
http://dx.doi.org/10.4103/ijabmr.IJABMR_397_17
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