Heart rate reduction after ivabradine might be associated with reverse electrical remodeling in patients with cardiomyopathy and left bundle branch block

Left bundle branch block increases the risk of death in patients with chronic heart failure. We herein report four clinical cases of patients with chronic heart failure caused by nonischemic cardiomyopathy with left bundle branch block that occurred when adding ivabradine to optimal medical therapy,...

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Autores principales: Kučerová, Andrea, Doškář, Petr, Dujka, Libor, Lekešová, Veronika, Volf, Petr, Koščová, Katarina, Neužil, Petr, Málek, Filip
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2018
Materias:
Case Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6259405/
https://www.ncbi.nlm.nih.gov/pubmed/30223689
http://dx.doi.org/10.1177/0300060518799566
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author Kučerová, Andrea
Doškář, Petr
Dujka, Libor
Lekešová, Veronika
Volf, Petr
Koščová, Katarina
Neužil, Petr
Málek, Filip
author_facet Kučerová, Andrea
Doškář, Petr
Dujka, Libor
Lekešová, Veronika
Volf, Petr
Koščová, Katarina
Neužil, Petr
Málek, Filip
author_sort Kučerová, Andrea
collection PubMed
description Left bundle branch block increases the risk of death in patients with chronic heart failure. We herein report four clinical cases of patients with chronic heart failure caused by nonischemic cardiomyopathy with left bundle branch block that occurred when adding ivabradine to optimal medical therapy, resulting in reverse electrical and mechanical remodeling. This phenomenon might be explained by the effect of ivabradine on reverse remodeling of the left ventricle with improvement of intraventricular conduction.
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spelling pubmed-62594052018-11-30 Heart rate reduction after ivabradine might be associated with reverse electrical remodeling in patients with cardiomyopathy and left bundle branch block Kučerová, Andrea Doškář, Petr Dujka, Libor Lekešová, Veronika Volf, Petr Koščová, Katarina Neužil, Petr Málek, Filip J Int Med Res Case Reports Left bundle branch block increases the risk of death in patients with chronic heart failure. We herein report four clinical cases of patients with chronic heart failure caused by nonischemic cardiomyopathy with left bundle branch block that occurred when adding ivabradine to optimal medical therapy, resulting in reverse electrical and mechanical remodeling. This phenomenon might be explained by the effect of ivabradine on reverse remodeling of the left ventricle with improvement of intraventricular conduction. SAGE Publications 2018-09-18 2018-11 /pmc/articles/PMC6259405/ /pubmed/30223689 http://dx.doi.org/10.1177/0300060518799566 Text en © The Author(s) 2018 http://creativecommons.org/licenses/by-nc/4.0/ Creative Commons Non Commercial CC BY-NC: This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (http://www.creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Case Reports
Kučerová, Andrea
Doškář, Petr
Dujka, Libor
Lekešová, Veronika
Volf, Petr
Koščová, Katarina
Neužil, Petr
Málek, Filip
Heart rate reduction after ivabradine might be associated with reverse electrical remodeling in patients with cardiomyopathy and left bundle branch block
title Heart rate reduction after ivabradine might be associated with reverse electrical remodeling in patients with cardiomyopathy and left bundle branch block
title_full Heart rate reduction after ivabradine might be associated with reverse electrical remodeling in patients with cardiomyopathy and left bundle branch block
title_fullStr Heart rate reduction after ivabradine might be associated with reverse electrical remodeling in patients with cardiomyopathy and left bundle branch block
title_full_unstemmed Heart rate reduction after ivabradine might be associated with reverse electrical remodeling in patients with cardiomyopathy and left bundle branch block
title_short Heart rate reduction after ivabradine might be associated with reverse electrical remodeling in patients with cardiomyopathy and left bundle branch block
title_sort heart rate reduction after ivabradine might be associated with reverse electrical remodeling in patients with cardiomyopathy and left bundle branch block
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6259405/
https://www.ncbi.nlm.nih.gov/pubmed/30223689
http://dx.doi.org/10.1177/0300060518799566
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