Cargando…

The Apoptotic Effect of 1’S-1’-Acetoxychavicol Acetate from Alpinia Conchigera on Human Cancer Cells

1’-(S)-1’-Acetoxychavicol acetate (ACA) isolated from the Malaysian ethno-medicinal plant Alpinia conchigera Griff. was investigated for its potential as an anticancer drug. In this communication, we describe the cytotoxic and apoptotic properties of ACA on five human tumour cell lines. Data from MT...

Descripción completa

Detalles Bibliográficos
Autores principales:	Awang, Khalijah, Azmi, Mohamad Nurul, Aun, Lionel In Lian, Aziz, Ahmad Nazif, Ibrahim, Halijah, Nagoor, Noor Hasima
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2010
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6259418/ https://www.ncbi.nlm.nih.gov/pubmed/21063268 http://dx.doi.org/10.3390/molecules15118048

Ejemplares similares

1’-Acetoxychavicol acetate inhibits growth of human oral carcinoma xenograft in mice and potentiates cisplatin effect via proinflammatory microenvironment alterations
por: In, Lionel LA, et al.
Publicado: (2012)

Anti-proliferative, apoptotic induction, and anti-migration effects of hemi-synthetic 1′S-1′-acetoxychavicol acetate analogs on MDA-MB-231 breast cancer cells
por: Liew, Su Ki, et al.
Publicado: (2017)

Suppression of microRNA-629 enhances sensitivity of cervical cancer cells to 1′S-1′-acetoxychavicol acetate via regulating RSU1
por: Phuah, Neoh Hun, et al.
Publicado: (2017)

Down-Regulation of MicroRNA-210 Confers Sensitivity towards 1’S-1’-Acetoxychavicol Acetate (ACA) in Cervical Cancer Cells by Targeting SMAD4
por: Phuah, Neoh Hun, et al.
Publicado: (2017)

The apoptotic effect of 1’S-1’-Acetoxychavicol Acetate (ACA) enhanced by inhibition of non-canonical autophagy in human non-small cell lung cancer cells
por: Sok, Sophia P. M., et al.
Publicado: (2017)

Recombinant human alpha fetoprotein synergistically potentiates the anti-cancer effects of 1′-S-1′-acetoxychavicol acetate when used as a complex against human tumours harbouring AFP-receptors
por: Arshad, Norhafiza M., et al.
Publicado: (2015)

Chemicals Constituents Isolated from Cultivate Alpinia conchigera Griff. and Antimicrobial Activity
por: Taib, Mohamad Nurul Azmi Mohamad, et al.
Publicado: (2020)

Essential Oil Composition and Antimicrobial Activities of Two Closely Related Species, Alpinia mutica Roxb. and Alpinia latilabris Ridl., from Peninsular Malaysia
por: Ibrahim, Halijah, et al.
Publicado: (2014)

Development and Evaluation of 1′-Acetoxychavicol Acetate (ACA)-Loaded Nanostructured Lipid Carriers for Prostate Cancer Therapy
por: Subramaniam, Bavani, et al.
Publicado: (2021)

1′-Acetoxychavicol Acetate Isolated from Alpinia galanga Ameliorates Ovalbumin-Induced Asthma in Mice
por: Seo, Joung-Wook, et al.
Publicado: (2013)

Correction: Regulation of Apoptotic Effects by Erythrocarpine E, a Cytotoxic Limonoid from Chisocheton erythrocarpus in HSC-4 Human Oral Cancer Cells
por: Nagoor, Noor Hasima, et al.
Publicado: (2011)

Regulation of Apoptotic Effects by Erythrocarpine E, a Cytotoxic Limonoid from Chisocheton erythrocarpus in HSC-4 Human Oral Cancer Cells
por: Nagoor, Noor Hasima, et al.
Publicado: (2011)

Cytotoxic activity of Alpinia murdochii Ridl.: A mountain ginger species from Peninsular Malaysia
por: Sim, Kae Shin, et al.
Publicado: (2014)

Inactivation of nuclear factor κB by MIP-based drug combinations augments cell death of breast cancer cells
por: Subramaniam, Menaga, et al.
Publicado: (2018)

Cytotoxic Effects of Pinnatane A Extracted from Walsura pinnata (Meliaceae) on Human Liver Cancer Cells
por: Zakaria, Nurhisyam, et al.
Publicado: (2018)

Geranylated 4-Phenylcoumarins Exhibit Anticancer Effects against Human Prostate Cancer Cells through Caspase-Independent Mechanism
por: Suparji, Noor Shahirah, et al.
Publicado: (2016)

7α-Hydroxy-β-Sitosterol from Chisocheton tomentosus Induces Apoptosis via Dysregulation of Cellular Bax/Bcl-2 Ratio and Cell Cycle Arrest by Downregulating ERK1/2 Activation
por: Tasyriq, Mohammad, et al.
Publicado: (2012)

Anti-Cancer Effects of Synergistic Drug–Bacterium Combinations on Induced Breast Cancer in BALB/c Mice
por: Subramaniam, Menaga, et al.
Publicado: (2019)

Cytotoxic and apoptotic effects of heat killed Mycobacterium indicus pranii (MIP) on various human cancer cell lines
por: Subramaniam, Menaga, et al.
Publicado: (2016)

Flavokavain B from the rhizome of Alpinia mutica Roxb
por: Sirat, Hasnah Mohd, et al.
Publicado: (2010)

Suppression of N‐Nitrosomethylbenzylamine‐induced Rat Esophageal Tumorigenesis by Dietary Feeding of 1′‐Acetoxychavicol Acetate
por: Kawabata, Kunihiro, et al.
Publicado: (2000)

In Vitro Activities of Enantiopure and Racemic 1′-Acetoxychavicol Acetate against Clinical Isolates of Mycobacterium tuberculosis
por: Warit, Saradee, et al.
Publicado: (2017)

Chemopreventive Effect of a Xanthine Oxidase Inhibitor, 1′‐Acetoxychavicol Acetate, on Rat Oral Carcinogenesis
por: Ohnishi, Masami, et al.
Publicado: (1996)

Chemoprevention of Azoxymethane‐induced Rat Colon Carcinogenesis by a Xanthine Oxidase Inhibitor, 1′‐Acetoxychavicol Acetate
por: Tanaka, Takuji, et al.
Publicado: (1997)

1′-Acetoxychavicol acetate promotes caspase 3-activated glioblastoma cell death by overcoming enhanced cytokine expression
por: WILLIAMS, MUSA, et al.
Publicado: (2013)

Natural Products for Cancer Therapy: A Review of Their Mechanism of Actions and Toxicity in the Past Decade
por: Ali Abdalla, Yasir Osman, et al.
Publicado: (2022)

Phytochemical and Cytotoxic Investigations of Alpinia mutica Rhizomes
por: Malek, Sri Nurestri Abdul, et al.
Publicado: (2011)

Inhibitory Effects of 1′‐Acetoxychavicol Acetate on N‐Nitrosobis(2‐oxopropyl)‐amine‐induced Initiation of Cholangiocarcinogenesis in Syrian Hamsters
por: Miyauchi, Makoto, et al.
Publicado: (2000)

Antioxidant potential, cytotoxic activity and total phenolic content of Alpinia pahangensis rhizomes
por: Phang, Chung-Weng, et al.
Publicado: (2013)

MicroRNA-6744-5p promotes anoikis in breast cancer and directly targets NAT1 enzyme
por: Malagobadan, Sharan, et al.
Publicado: (2020)

MiR-378 and MiR-1827 Regulate Tumor Invasion, Migration and Angiogenesis in Human Lung Adenocarcinoma by Targeting RBX1 and CRKL, Respectively
por: Ho, Chai San, et al.
Publicado: (2018)

The Role of microRNAs in the Regulation of Apoptosis in Lung Cancer and Its Application in Cancer Treatment
por: Othman, Norahayu, et al.
Publicado: (2014)

Evaluation of MicroRNAs Regulating Anoikis Pathways and Its Therapeutic Potential
por: Malagobadan, Sharan, et al.
Publicado: (2015)

Effects of the tropical ginger compound,1’-acetoxychavicol acetate, against tumor promotion in K5.Stat3C transgenic mice
por: Batra, Vinita, et al.
Publicado: (2012)

Regulation of MicroRNAs by Natural Agents: New Strategies in Cancer Therapies
por: Phuah, Neoh Hun, et al.
Publicado: (2014)

Cytotoxic effect of Alpinia scabra (Blume) Náves extracts on human breast and ovarian cancer cells
por: Reddy, Annushuya Subba, et al.
Publicado: (2013)

TM-233, a novel analog of 1′-acetoxychavicol acetate, induces cell death in myeloma cells by inhibiting both JAK/STAT and proteasome activities
por: Sagawa, Morihiko, et al.
Publicado: (2015)

Methyl 3-acetoxy-3-dehydroxyursolate
por: Abdullah, Nor Hayati, et al.
Publicado: (2009)

Complete Chloroplast Genome Analysis of Two Important Medicinal Alpinia Species: Alpinia galanga and Alpinia kwangsiensis
por: Zhang, Yue, et al.
Publicado: (2021)

A Review of the Structure—Activity Relationship of Natural and Synthetic Antimetastatic Compounds
por: Liew, Su Ki, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_cvsip4b0p3muf0v09mhacu3591