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Peptide Phage Display as a Tool for Drug Discovery: Targeting Membrane Receptors

Ligands selected from phage-displayed random peptide libraries tend to be directed to biologically relevant sites on the surface of the target protein. Consequently, peptides derived from library screenings often modulate the target protein’s activity in vitro and in vivo and can be used as lead com...

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Detalles Bibliográficos
Autores principales: Molek, Peter, Strukelj, Borut, Bratkovic, Tomaz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6259427/
https://www.ncbi.nlm.nih.gov/pubmed/21258295
http://dx.doi.org/10.3390/molecules16010857