Reduction of Diphenyl Diselenide and Analogs by Mammalian Thioredoxin Reductase Is Independent of Their Gluthathione Peroxidase-Like Activity: A Possible Novel Pathway for Their Antioxidant Activity

Since the successful use of the organoselenium drug ebselen in clinical trials for the treatment of neuropathological conditions associated with oxidative stress, there have been concerted efforts geared towards understanding the precise mechanism of action of ebselen and other organoselenium compou...

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Detalles Bibliográficos
Autores principales: de Freitas, Andressa Sausen, Prestes, Alessandro de Souza, Wagner, Caroline, Sudati, Jéssie Haigert, Alves, Diego, Porciúncula, Lisiane Oliveira, Kade, Ige Joseph, Rocha, João Batista Teixeira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6259470/
https://www.ncbi.nlm.nih.gov/pubmed/21030914
http://dx.doi.org/10.3390/molecules15117699

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