Crystal Structure and Hydrogen Bonding Study of (10E)-2,2-Dimethyl-3,4-dihydro-2H-benzo[g]chromene-5,10-dione 10-Oxime Derived From α-Lapachone

The compound (10E)-2,2-dimethyl-3,4-dihydro-2H-benzo[g]chromene-5,10-dione-10-oxime (1) was synthesized from α-lapachone and hydroxylamine chloride in alkaline medium. Single-crystals suitable for X-ray diffraction measurements were grown from an ethanol solution, and the crystal structure of the ti...

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Autores principales: da Silva, Andrea R., Herbst, Marcelo H., Ferreira, Aurelio B. B., da Silva, Ari M., Visentin, Lorenzo C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6259599/
https://www.ncbi.nlm.nih.gov/pubmed/21273950
http://dx.doi.org/10.3390/molecules16021192
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author da Silva, Andrea R.
Herbst, Marcelo H.
Ferreira, Aurelio B. B.
da Silva, Ari M.
Visentin, Lorenzo C.
author_facet da Silva, Andrea R.
Herbst, Marcelo H.
Ferreira, Aurelio B. B.
da Silva, Ari M.
Visentin, Lorenzo C.
author_sort da Silva, Andrea R.
collection PubMed
description The compound (10E)-2,2-dimethyl-3,4-dihydro-2H-benzo[g]chromene-5,10-dione-10-oxime (1) was synthesized from α-lapachone and hydroxylamine chloride in alkaline medium. Single-crystals suitable for X-ray diffraction measurements were grown from an ethanol solution, and the crystal structure of the title molecule is reported for the first time. The title molecule was also characterized by (1)H- and (13)C-NMR in CDCl(3) solution, FTIR and MS. The crystal structure of 1 shows an E stereochemistry and dimers formed through classical hydrogen bonds.
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spelling pubmed-62595992018-12-20 Crystal Structure and Hydrogen Bonding Study of (10E)-2,2-Dimethyl-3,4-dihydro-2H-benzo[g]chromene-5,10-dione 10-Oxime Derived From α-Lapachone da Silva, Andrea R. Herbst, Marcelo H. Ferreira, Aurelio B. B. da Silva, Ari M. Visentin, Lorenzo C. Molecules Article The compound (10E)-2,2-dimethyl-3,4-dihydro-2H-benzo[g]chromene-5,10-dione-10-oxime (1) was synthesized from α-lapachone and hydroxylamine chloride in alkaline medium. Single-crystals suitable for X-ray diffraction measurements were grown from an ethanol solution, and the crystal structure of the title molecule is reported for the first time. The title molecule was also characterized by (1)H- and (13)C-NMR in CDCl(3) solution, FTIR and MS. The crystal structure of 1 shows an E stereochemistry and dimers formed through classical hydrogen bonds. MDPI 2011-01-27 /pmc/articles/PMC6259599/ /pubmed/21273950 http://dx.doi.org/10.3390/molecules16021192 Text en © 2011 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Article
da Silva, Andrea R.
Herbst, Marcelo H.
Ferreira, Aurelio B. B.
da Silva, Ari M.
Visentin, Lorenzo C.
Crystal Structure and Hydrogen Bonding Study of (10E)-2,2-Dimethyl-3,4-dihydro-2H-benzo[g]chromene-5,10-dione 10-Oxime Derived From α-Lapachone
title Crystal Structure and Hydrogen Bonding Study of (10E)-2,2-Dimethyl-3,4-dihydro-2H-benzo[g]chromene-5,10-dione 10-Oxime Derived From α-Lapachone
title_full Crystal Structure and Hydrogen Bonding Study of (10E)-2,2-Dimethyl-3,4-dihydro-2H-benzo[g]chromene-5,10-dione 10-Oxime Derived From α-Lapachone
title_fullStr Crystal Structure and Hydrogen Bonding Study of (10E)-2,2-Dimethyl-3,4-dihydro-2H-benzo[g]chromene-5,10-dione 10-Oxime Derived From α-Lapachone
title_full_unstemmed Crystal Structure and Hydrogen Bonding Study of (10E)-2,2-Dimethyl-3,4-dihydro-2H-benzo[g]chromene-5,10-dione 10-Oxime Derived From α-Lapachone
title_short Crystal Structure and Hydrogen Bonding Study of (10E)-2,2-Dimethyl-3,4-dihydro-2H-benzo[g]chromene-5,10-dione 10-Oxime Derived From α-Lapachone
title_sort crystal structure and hydrogen bonding study of (10e)-2,2-dimethyl-3,4-dihydro-2h-benzo[g]chromene-5,10-dione 10-oxime derived from α-lapachone
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6259599/
https://www.ncbi.nlm.nih.gov/pubmed/21273950
http://dx.doi.org/10.3390/molecules16021192
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