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A characteristic signature of insulin-like growth factor (IGF) axis expression during osteogenic differentiation of human dental pulp cells (hDPCs): Potential co-ordinated regulation of IGF action
The IGF axis is represented by two growth factors (IGF1 and IGF2), two cognate cell surface receptors (IGF1R and IGF2R), six soluble high affinity IGF binding proteins (IGFBP1-6) and several IGFBP proteases. IGF1 and IGF2 are present at high concentrations in bone and play a crucial role in the main...
Autores principales: | Al-Khafaji, Hasanain, Noer, Pernille R., Alkharobi, Hanna, Alhodhodi, Aishah, Meade, Josephine, El-Gendy, Reem, Oxvig, Claus, Beattie, James |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6259625/ https://www.ncbi.nlm.nih.gov/pubmed/30071469 http://dx.doi.org/10.1016/j.ghir.2018.07.003 |
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