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Enhancement of Pneumocandin B(0) Production in Glarea lozoyensis by Low-Temperature Adaptive Laboratory Evolution
The production of pneumocandin B(0) is limited by feedback inhibition. Here, low-temperature adaptive laboratory evolution (ALE) was used to improve the production capacity of Glarea lozoyensis by enhancing its membrane permeability. After 50 cycles of ALE, the pneumocandin B(0) production of the en...
Autores principales: | Song, Ping, Zhang, Ke, Zhang, Sen, Huang, Bao-Qi, Ji, Xiao-Jun, Ren, Lu-Jing, Gao, Song, Wen, Jian-Ping, Huang, He |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6259640/ https://www.ncbi.nlm.nih.gov/pubmed/30519220 http://dx.doi.org/10.3389/fmicb.2018.02788 |
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