QSAR Models for CXCR2 Receptor Antagonists Based on the Genetic Algorithm for Data Preprocessing Prior to Application of the PLS Linear Regression Method and Design of the New Compounds Using In Silico Virtual Screening

The CXCR2 receptors play a pivotal role in inflammatory disorders and CXCR2 receptor antagonists can in principle be used in the treatment of inflammatory and related diseases. In this study, quantitative relationships between the structures of 130 antagonists of the CXCR2 receptors and their activi...

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Detalles Bibliográficos
Autores principales: Asadollahi, Tahereh, Dadfarnia, Shayessteh, Shabani, Ali Mohammad Haji, Ghasemi, Jahan B., Sarkhosh, Maryam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6259643/
https://www.ncbi.nlm.nih.gov/pubmed/21358586
http://dx.doi.org/10.3390/molecules16031928

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