Synthesis and Biological Evaluation of 4-Aroyl-6,7,8-Trimethoxyquinolines as a Novel Class of Anticancer Agents

A series of 2-aroyl and 2-aryl-5,6,7-trimethoxyquinoline and 4-aroyl-6,7,8-trimethoxyquinoline combretastatin analogs were synthesized and evaluated for their potential anticancer activity. The 4-aroylquinoline 11 inhibited the growth of the human cancer cells lines KB, HT-29, and MKN45, as well as...

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Detalles Bibliográficos
Autores principales: Hsieh, Cheng-Chih, Lee, Hsueh-Yun, Nien, Chih-Ying, Kuo, Ching-Chuan, Chang, Chi-Yen, Chang, Jang-Yang, Liou, Jing-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6259658/
https://www.ncbi.nlm.nih.gov/pubmed/21383664
http://dx.doi.org/10.3390/molecules16032274

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6259658/
https://www.ncbi.nlm.nih.gov/pubmed/21383664
http://dx.doi.org/10.3390/molecules16032274

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