In Vitro and In Vivo Antioxidant Activity of a Water-Soluble Polysaccharide from Dendrobium denneanum

The water-soluble crude polysaccharide (DDP) obtained from the aqueous extracts of the stem of Dendrobium denneanum through hot water extraction followed by ethanol precipitation, was found to have an average molecular weight (Mw) of about 484.7 kDa. Monosaccharide analysis revealed that DDP was com...

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Autores principales: Luo, Aoxue, Ge, Zhongfu, Fan, Yijun, Luo, Aoshuang, Chun, Ze, He, XingJin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6259659/
https://www.ncbi.nlm.nih.gov/pubmed/21321529
http://dx.doi.org/10.3390/molecules16021579
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author Luo, Aoxue
Ge, Zhongfu
Fan, Yijun
Luo, Aoshuang
Chun, Ze
He, XingJin
author_facet Luo, Aoxue
Ge, Zhongfu
Fan, Yijun
Luo, Aoshuang
Chun, Ze
He, XingJin
author_sort Luo, Aoxue
collection PubMed
description The water-soluble crude polysaccharide (DDP) obtained from the aqueous extracts of the stem of Dendrobium denneanum through hot water extraction followed by ethanol precipitation, was found to have an average molecular weight (Mw) of about 484.7 kDa. Monosaccharide analysis revealed that DDP was composed of arabinose, xylose, mannose, glucose and galactose in a molar ratio of 1.00:2.66:8.92:34.20:10.16. The investigation of antioxidant activity both in vitro and in vivo showed that DDP is a potential antioxidant.
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spelling pubmed-62596592018-12-20 In Vitro and In Vivo Antioxidant Activity of a Water-Soluble Polysaccharide from Dendrobium denneanum Luo, Aoxue Ge, Zhongfu Fan, Yijun Luo, Aoshuang Chun, Ze He, XingJin Molecules Article The water-soluble crude polysaccharide (DDP) obtained from the aqueous extracts of the stem of Dendrobium denneanum through hot water extraction followed by ethanol precipitation, was found to have an average molecular weight (Mw) of about 484.7 kDa. Monosaccharide analysis revealed that DDP was composed of arabinose, xylose, mannose, glucose and galactose in a molar ratio of 1.00:2.66:8.92:34.20:10.16. The investigation of antioxidant activity both in vitro and in vivo showed that DDP is a potential antioxidant. MDPI 2011-02-14 /pmc/articles/PMC6259659/ /pubmed/21321529 http://dx.doi.org/10.3390/molecules16021579 Text en © 2011 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Article
Luo, Aoxue
Ge, Zhongfu
Fan, Yijun
Luo, Aoshuang
Chun, Ze
He, XingJin
In Vitro and In Vivo Antioxidant Activity of a Water-Soluble Polysaccharide from Dendrobium denneanum
title In Vitro and In Vivo Antioxidant Activity of a Water-Soluble Polysaccharide from Dendrobium denneanum
title_full In Vitro and In Vivo Antioxidant Activity of a Water-Soluble Polysaccharide from Dendrobium denneanum
title_fullStr In Vitro and In Vivo Antioxidant Activity of a Water-Soluble Polysaccharide from Dendrobium denneanum
title_full_unstemmed In Vitro and In Vivo Antioxidant Activity of a Water-Soluble Polysaccharide from Dendrobium denneanum
title_short In Vitro and In Vivo Antioxidant Activity of a Water-Soluble Polysaccharide from Dendrobium denneanum
title_sort in vitro and in vivo antioxidant activity of a water-soluble polysaccharide from dendrobium denneanum
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6259659/
https://www.ncbi.nlm.nih.gov/pubmed/21321529
http://dx.doi.org/10.3390/molecules16021579
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