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Lignans and Other Constituents from Aerial Parts of Haplophyllum Villosum

During our phytochemical investigation of Haplophyllum villosum (Rutaceae), a perennial herb from Iran, a new 4,8-diaryl-3,7-dioxobicyclo-(3,3,0)-octane type lignan, eudesmin A (1), together with four known compounds–eudesmin (2), haplamine (3), umbelliferone (4) and scopoletin (5)–were isolated fro...

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Detalles Bibliográficos
Autores principales: Parhoodeh, Parimah, Rahmani, Mawardi, Hashim, Najihah Mohd, Sukari, Mohd Aspollah, Cheng Lian, Gwendoline Ee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6259757/
https://www.ncbi.nlm.nih.gov/pubmed/21383663
http://dx.doi.org/10.3390/molecules16032268
Descripción
Sumario:During our phytochemical investigation of Haplophyllum villosum (Rutaceae), a perennial herb from Iran, a new 4,8-diaryl-3,7-dioxobicyclo-(3,3,0)-octane type lignan, eudesmin A (1), together with four known compounds–eudesmin (2), haplamine (3), umbelliferone (4) and scopoletin (5)–were isolated from aerial parts of the plant. The structures of the compounds were elucidated using NMR spectral analysis ((1)H-NMR,(13)C-NMR, HSQC, COSY and HMBC) as well as UV, IR and MS spectra and comparison with previously reported data.