Antitrypanosomal Activity of Novel Benzaldehyde-Thiosemicarbazone Derivatives from Kaurenoic Acid (†)

A series of new thiosemicarbazones derived from natural diterpene kaurenoic acid were synthesized and tested against the epimastigote forms of Trypanosoma cruzi to evaluate their antitrypanosomal potential. Seven of the synthesized thiosemicarbazones were more active than kaurenoic acid with IC(50)...

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Detalles Bibliográficos
Autores principales: Haraguchi, Shirani K., Silva, Adriano A., Vidotti, Gentil J., dos Santos, Phercyles V., Garcia, Francielle P., Pedroso, Raissa B., Nakamura, Celso V., de Oliveira, Cecília M. A., da Silva, Cleuza C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6259918/
https://www.ncbi.nlm.nih.gov/pubmed/21270733
http://dx.doi.org/10.3390/molecules16021166

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