Chlorination and oxidation of the extracellular matrix protein laminin and basement membrane extracts by hypochlorous acid and myeloperoxidase

Basement membranes are specialized extracellular matrices that underlie arterial wall endothelial cells, with laminin being a key structural and biologically-active component. Hypochlorous acid (HOCl), a potent oxidizing and chlorinating agent, is formed in vivo at sites of inflammation via the enzy...

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Detalles Bibliográficos
Autores principales: Nybo, Tina, Dieterich, Simon, Gamon, Luke F., Chuang, Christine Y., Hammer, Astrid, Hoefler, Gerald, Malle, Ernst, Rogowska-Wrzesinska, Adelina, Davies, Michael J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6260226/
https://www.ncbi.nlm.nih.gov/pubmed/30476874
http://dx.doi.org/10.1016/j.redox.2018.10.022

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