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Chlorination and oxidation of the extracellular matrix protein laminin and basement membrane extracts by hypochlorous acid and myeloperoxidase
Basement membranes are specialized extracellular matrices that underlie arterial wall endothelial cells, with laminin being a key structural and biologically-active component. Hypochlorous acid (HOCl), a potent oxidizing and chlorinating agent, is formed in vivo at sites of inflammation via the enzy...
Autores principales: | Nybo, Tina, Dieterich, Simon, Gamon, Luke F., Chuang, Christine Y., Hammer, Astrid, Hoefler, Gerald, Malle, Ernst, Rogowska-Wrzesinska, Adelina, Davies, Michael J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6260226/ https://www.ncbi.nlm.nih.gov/pubmed/30476874 http://dx.doi.org/10.1016/j.redox.2018.10.022 |
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