Three-Dimensional Organoids Reveal Therapy Resistance of Esophageal and Oropharyngeal Squamous Cell Carcinoma Cells

BACKGROUND & AIMS: Oropharyngeal and esophageal squamous cell carcinomas, especially the latter, are a lethal disease, featuring intratumoral cancer cell heterogeneity and therapy resistance. To facilitate cancer therapy in personalized medicine, three-dimensional (3D) organoids may be useful fo...

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Detalles Bibliográficos
Autores principales: Kijima, Takashi, Nakagawa, Hiroshi, Shimonosono, Masataka, Chandramouleeswaran, Prasanna M., Hara, Takeo, Sahu, Varun, Kasagi, Yuta, Kikuchi, Osamu, Tanaka, Koji, Giroux, Veronique, Muir, Amanda B., Whelan, Kelly A., Ohashi, Shinya, Naganuma, Seiji, Klein-Szanto, Andres J., Shinden, Yoshiaki, Sasaki, Ken, Omoto, Itaru, Kita, Yoshiaki, Muto, Manabu, Bass, Adam J., Diehl, J. Alan, Ginsberg, Gregory G., Doki, Yuichiro, Mori, Masaki, Uchikado, Yasuto, Arigami, Takaaki, Avadhani, Narayan G., Basu, Devraj, Rustgi, Anil K., Natsugoe, Shoji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6260338/
https://www.ncbi.nlm.nih.gov/pubmed/30510992
http://dx.doi.org/10.1016/j.jcmgh.2018.09.003

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