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Ezh2 Controls Skin Tolerance through Distinct Mechanisms in Different Subsets of Skin Dendritic Cells

Ezh2, a well-established epigenetic repressor, can down-regulate leukocyte inflammatory responses, but its role in cutaneous health remains elusive. Here we demonstrate that Ezh2 controls cutaneous tolerance by regulating Langerhans cell (LC) transmigration across the epidermal basement membrane dir...

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Detalles Bibliográficos
Autores principales:	Loh, Jia Tong, Lim, Thomas Jun Feng, Ikumi, Kyoko, Matoba, Takuma, Janela, Baptiste, Gunawan, Merry, Toyama, Tatsuya, Bunjamin, Maegan, Ng, Lai Guan, Poidinger, Michael, Morita, Akimichi, Ginhoux, Florent, Yamazaki, Sayuri, Lam, Kong-Peng, Su, I-hsin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6260444/ https://www.ncbi.nlm.nih.gov/pubmed/30496973 http://dx.doi.org/10.1016/j.isci.2018.11.019

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