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Comparison of Germline versus Somatic BAP1 Mutations for Risk of Metastasis in Uveal Melanoma

BACKGROUND: Germline mutations in BAP1 have been associated with BAP1-Tumor Predisposition Syndrome (BAP1-TPDS), a predisposition to multiple tumors within a family that includes uveal melanoma (UM), cutaneous melanoma, malignant mesothelioma and renal cell carcinoma. Alternatively, somatic mutation...

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Detalles Bibliográficos
Autores principales:	Ewens, K. G., Lalonde, E., Richards-Yutz, J., Shields, C. L., Ganguly, A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6260582/ https://www.ncbi.nlm.nih.gov/pubmed/30477459 http://dx.doi.org/10.1186/s12885-018-5079-x

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