Cargando…

Syntheses, Structures and Antimicrobial Activities of bis(Imino)acenaphthene (BIAN) Imidazolium Salts

The syntheses of four new bis(imino)acenaphthene (BIAN) imidazolium chlorides are reported, three of which have been structurally characterized. The synthesis of a new, structurally authenticated BIAN ligand is also described. We report the results of the use of these BIAN imidazolium salts as antim...

Descripción completa

Detalles Bibliográficos
Autores principales: Butorac, Rachel R., Al-Deyab, Salem S., Cowley, Alan H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6260596/
https://www.ncbi.nlm.nih.gov/pubmed/21499218
http://dx.doi.org/10.3390/molecules16043168
_version_ 1783374827204116480
author Butorac, Rachel R.
Al-Deyab, Salem S.
Cowley, Alan H.
author_facet Butorac, Rachel R.
Al-Deyab, Salem S.
Cowley, Alan H.
author_sort Butorac, Rachel R.
collection PubMed
description The syntheses of four new bis(imino)acenaphthene (BIAN) imidazolium chlorides are reported, three of which have been structurally characterized. The synthesis of a new, structurally authenticated BIAN ligand is also described. We report the results of the use of these BIAN imidazolium salts as antimicrobials against the pathogens S. aureus, B. subtilis, E. coli and P. aeruginosa. The antimicrobial efficacies were particularly high for the N-(2,6-diisopropylphenyl)- and N-(mesityl)- substituted BIAN imidazolium salts (MIC values < 0.6 μg/mL).
format Online
Article
Text
id pubmed-6260596
institution National Center for Biotechnology Information
language English
publishDate 2011
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-62605962018-12-10 Syntheses, Structures and Antimicrobial Activities of bis(Imino)acenaphthene (BIAN) Imidazolium Salts Butorac, Rachel R. Al-Deyab, Salem S. Cowley, Alan H. Molecules Article The syntheses of four new bis(imino)acenaphthene (BIAN) imidazolium chlorides are reported, three of which have been structurally characterized. The synthesis of a new, structurally authenticated BIAN ligand is also described. We report the results of the use of these BIAN imidazolium salts as antimicrobials against the pathogens S. aureus, B. subtilis, E. coli and P. aeruginosa. The antimicrobial efficacies were particularly high for the N-(2,6-diisopropylphenyl)- and N-(mesityl)- substituted BIAN imidazolium salts (MIC values < 0.6 μg/mL). MDPI 2011-04-15 /pmc/articles/PMC6260596/ /pubmed/21499218 http://dx.doi.org/10.3390/molecules16043168 Text en © 2011 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Article
Butorac, Rachel R.
Al-Deyab, Salem S.
Cowley, Alan H.
Syntheses, Structures and Antimicrobial Activities of bis(Imino)acenaphthene (BIAN) Imidazolium Salts
title Syntheses, Structures and Antimicrobial Activities of bis(Imino)acenaphthene (BIAN) Imidazolium Salts
title_full Syntheses, Structures and Antimicrobial Activities of bis(Imino)acenaphthene (BIAN) Imidazolium Salts
title_fullStr Syntheses, Structures and Antimicrobial Activities of bis(Imino)acenaphthene (BIAN) Imidazolium Salts
title_full_unstemmed Syntheses, Structures and Antimicrobial Activities of bis(Imino)acenaphthene (BIAN) Imidazolium Salts
title_short Syntheses, Structures and Antimicrobial Activities of bis(Imino)acenaphthene (BIAN) Imidazolium Salts
title_sort syntheses, structures and antimicrobial activities of bis(imino)acenaphthene (bian) imidazolium salts
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6260596/
https://www.ncbi.nlm.nih.gov/pubmed/21499218
http://dx.doi.org/10.3390/molecules16043168
work_keys_str_mv AT butoracrachelr synthesesstructuresandantimicrobialactivitiesofbisiminoacenaphthenebianimidazoliumsalts
AT aldeyabsalems synthesesstructuresandantimicrobialactivitiesofbisiminoacenaphthenebianimidazoliumsalts
AT cowleyalanh synthesesstructuresandantimicrobialactivitiesofbisiminoacenaphthenebianimidazoliumsalts